引用

两核reuniens和丘脑前核与内侧皮质和海马区域人口相互连接,连接反映各自的贡献,学习和记忆。更好地欣赏他们的角色比较,对不同逆行示踪剂放置在这两个在成年大鼠丘脑的网站。丘脑的网站接收温和的皮质层V输入,与第六层的密度预测。尽管经常重叠在第六层,腹侧前额叶和前扣带输入核reuniens集中在最深的子层(VIb)。同时,输入前丘脑核是通过和VIb两次层更均匀,因此他们通常位于表面上比原子核reuniens的预测。再次,许多海马(菌丝层)神经元投射到核reuniens和丘脑前核部分混合深层细胞部分菌丝层内,细胞的核reuniens一直倾向于说谎更深,即。,立即毗邻alveus。变量的数量double-labelled细胞出现在那些皮质和subicular两部分细胞种群混合,虽然他们仍在少数。我们的数据也显示预测这两个丘脑的网站是如何组织在反对背腹侧和吻侧/尾/梯度在大脑皮层和海马结构。在丘脑前核优先受背侧皮层支配网站,更多的腹侧额叶网站优先达到reuniens核。这些解剖上的差异可能支撑这两个丘脑领域的互补的认知功能。意义statementBoth reuniens和丘脑前核核联系额叶皮质与海马结构。 We show that the cortical and hippocampal projections to these thalamic sites show intermingled but opposing gradients of origin across the cerebral cortex (anterior thalamic – more dorsal, nucleus reuniens – more ventral), with their respective afferents typically arising from different neurons. There is also a repeated tendency across cortical areas for nucleus reuniens inputs to arise from the very deepest layer (VIb), while anterior thalamic inputs are often slightly more superficial, located across VIb and VIa. A similar depth distinction is again seen in the subiculum. These patterns indicate a separation of information reaching these two thalamic sites, alongside functional divisions within cortical layer VI.