引用

孤立束(NST)的核处理味觉和相关的体感信息的吻和一般的内脏感觉信息尾。为了比较其与其他啮齿类动物的连接，本研究在C57BL/6J小鼠中提供了NST的核下细胞结构分块(Nissl染色)，分为吻侧、中间和尾侧。亚核进一步通过NADPH染色和P2X2免疫反应(IR)进行表征。霍乱毒素B亚单位(CTb)标记显示NST亚核接受鼓膜索神经(CT)传入，与臂旁核(PBN)和网状结构(RF)连接，以及相互连接。CT终端在吻侧中央(RC)和内侧(M)亚核最为密集;吻侧侧(RL)亚核密度较低;腹侧亚核(V)、腹侧亚核(VL)和中央侧亚核(CL)稀疏。CTb注入PBN逆行标记上述亚核中的细胞;RC和M提供PBN投影神经元的最大来源。桥脑传出轴突主要终止于V和吻侧内侧(RM)亚核。 CTb injection into the medullary RF labels cells and axonal endings predominantly in V at rostral and intermediate NST levels. Small CTb injections within the NST label extensive projections from the rostral division to caudal subnuclei. Projections from the caudal division primarily interconnect subnuclei confined to the caudal division of the NST; they also connect with the area postrema. P2X2 -IR identifies probable vagal nerve terminals in the central (Ce) subnucleus in the intermediate/caudal NST. Ce also shows intense NADPH staining and does not project to the PBN.